At night, the Apocalyptic Horseman cannot be killed. Each night, the Apocalyptic Horseman may attack a player. The Horsemen win when everyone else is dead.

When all remaining Horsemen are united and all remaining players doomed, Doomsday is unleashed, and all Horsemen turn into an Apocalyptic Horseman. Apocalyptic Horseman cannot be killed in any way during the night. Attacking a player is an end-night ability. The Apocalyptic Horseman may not kill another player, if they have already attempted to doom somebody in the same night.

Each night, the Apothecary may poison a player, killing them at the end of the next night. Alternatively, they may cure the player they last poisoned.

The Apothecary starts the game with three flasks of poison and a single antidote. When the Apothecary poisons a player, that player will be killed at the end of the next night (this is not an attack). Poison is applied at start day, so the Apothecary will only poison a player if the Apothecary survives the night. Instead of poisoning a player, the Apothecary may also use their antidote to cure the player they have previously poisoned, saving them from death. Players are not notified of being poisoned or cured. Both actions are immediate abilities.