At the start of the game, the Psychopath is given an arbitrary list with one third of the town’s population, rounded up, on it. If all players on that list are dead, and the Psychopath is still alive, the Psychopath wins.

When the Psychopath wins, the Psychopath ascends and stops playing. The game continues. The Psychopath can’t win when they are dead. The Psychopath's list will always contain at least one player from every team that has at least two players. The Psychopath may strongly disguise themself as any role. The disguise is applied immediately. They can update this disguise once per phase, with 1 emergency change to be used whenever the Psychopath wants to. If the Psychopath changes role, the disguise is lost. Additionally, the Psychopath may choose to either investigate or weakly disguise a player each day, but not both. Their investigation is affected by all disguises, redirections and obstructions. Their disguise lasts for the current and next phase.

The Plague Doctor is mostly immune to the plague bearer’s disease and requires the plague team to be eliminated in order to win. Each night, they may check a player for symptoms of the plague. Additionally, they are also able to cure players.

As soon as the plague team is eliminated, the Plague Doctor ascends and wins. The Plague Doctor cannot win while dead. Each night, the Plague Doctor may check a player for symptoms of the plague. The Plague Doctor will immediately be informed if and since when their target has had the plague. Members of the plague team do not have any symptoms and will never show up as having the plague. The Plague Doctor starts off with vials that can cure the plague. They have one vial for every five players in the game (rounded). Each night, the Plague Doctor may also choose to use one of their vials to immediately cure a player. Cured players no longer have the plague and stop being contagious, however they will not be informed of this. A player that is already in the final stage of the plague (i.e. they have already been informed that they have it) is too far gone to be saved and can not be cured anymore.

If the plague bearer attempts to contaminate the Plague Doctor with one of their rodents, the Plague Doctor immediately dies (not an attack). Otherwise, the Plague Doctor is immune to the disease. The Plague team cannot win while a Plague Doctor is alive.