The Plague Carrier wins with the plague bearers and joins a channel with them to communicate securely.

The Plague Carrier does not have any special abilities. If somebody tries to copy a plague bearer a Plague Carrier is created instead. The Plague Carrier can be a carrier of the plague but once they become contaminated they don't die and instead stay contagious for the rest of the game. The plague bearer may not attempt to directly contaminate the Plague Carrier using one of their rodents. The Plague Carrier cannot win while a Plague Doctor is alive. If the last plague bearer dies, and there are rodents left, the Plague Carrier stops being contagious and becomes a plague bearer. At the start of every phase, the Plague Carrier is told the amount of contagious players.

The Plague Bearer's disease is lethal and highly contagious. Their desire is to kill off all other players.

The Plague Bearer starts the game with rodents that carry the plague. They have one rodent for every five players in the game (rounded). If there are several Plague Bearers then they know each other, and their rodent counts are combined. Each Plague Bearer may use one rodent per night. Each night, the Plague Bearer may free one of their rodents to contaminate another player. Contaminated players will be affected by the disease. The Plague Bearer cannot be contaminated. If the Plague Bearer attempts to contaminate an already contaminated player, they are informed, but the rodent is still used up. Contaminating a player is an immediate ability. Contaminated players are contagious, and remain so till their death. Any player who visits or is visited by a contagious player is immediately contaminated. Any type of action (target, attack, investigation, etc) is counted as a visit. At the start of the second night after being contaminated the player is informed that they are contaminated.

At the end of the second night after being contaminated the player will stop being contagious and die. This is not an attack. Should the player still be alive afterwards, they remain contagious, but will not die again. If no members of the plague team or channel remain, all players are no longer contaminated, although they are not informed about this. If the Plague Bearer attempts to use a rodent on the Plague Doctor, the attempt fails, the Plague Doctor immediately dies (not an attack), and the rodent is not used up. The Plague Bearer cannot win while a Plague Doctor is alive.

At the end of Day 0, the Horseman becomes one of the other Horseman roles.

The Horseman can not immediately become an Apocalyptic Horseman. Each Horseman can doom a player every night, the effect of which depends on the type of Horseman. When a Horseman attempts to doom another Horseman it fails and the two Horsemen unite, joining a shared channel. Doomed players are informed that they have been doomed, but not which Horseman doomed them. Doomed players can be doomed again by the same or a different Horseman. When all remaining Horsemen are united and all remaining players doomed, Doomsday is unleashed: all Horsemen turn into Apocalyptic Horsemen, with the ability to attack a player each night. The Horsemen win when everyone else is dead.